Biolistics for high-throughput transformation and RNA interference inDrosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Discovery of novel targets with high throughput RNA interference screening.
High throughput technologies have the potential to affect all aspects of drug discovery. Considerable attention is paid to high throughput screening (HTS) for small molecule lead compounds. The identification of the targets that enter those HTS campaigns had been driven by basic research until the advent of genomics level data acquisition such as sequencing and gene expression microarrays. Larg...
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BACKGROUND High-throughput RNA interference (RNAi) screening has become a widely used approach to elucidating gene functions. However, analysis and annotation of large data sets generated from these screens has been a challenge for researchers without a programming background. Over the years, numerous data analysis methods were produced for plate quality control and hit selection and implemente...
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ژورنال
عنوان ژورنال: Fly
سال: 2008
ISSN: 1933-6934,1933-6942
DOI: 10.4161/fly.6985